Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Calories
<5
Total Carbohydrate
<1 g
<1%**
Total Sugars
0 g
†
Includes 0 g Added Sugars
0%**
Xylitol
<1 g
†
Vitamin C (as Ascorbic Acid)
100 mg
111%
Zinc (elemental) (from 15 mg Zinc Bisglycinate) (TRAACS™)
3 mg
27%
Elderberry (10:1 Concentrate)(Sambucus nigra) (Fruit)
150 mg
†
Top Medical Research Studies
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
9
We explored the impact of an anthocyanin-rich black elderberry extract on high cholesterol by conducting a study with apoE(-/-) mice, which are a common model for high cholesterol and HDL dysfunction. Over a period of six weeks, these mice received a diet supplemented with this black elderberry extract while a control group maintained a normal diet.
Our findings were quite promising. Although we didn’t see significant differences in overall serum lipids after six weeks, we did notice improvements in several key markers associated with HDL function. The BEE-fed mice exhibited higher levels of beneficial paraoxonase-1 (PON1) activity, which is important for heart health, as well as reductions in liver aspartate transaminase and fasting glucose levels.
Furthermore, the BEE-fed mice had significantly lower levels of a chemokine linked to inflammation, which is beneficial as chronic inflammation can negatively impact cholesterol levels. Most notably, we found reduced total cholesterol levels in the aorta of the elderberry-fed mice, suggesting a slowdown in the progression of atherosclerosis. Overall, this study indicates that black elderberry could potentially help improve HDL function and support the management of high cholesterol as part of a dietary approach.
Our findings were quite promising. Although we didn’t see significant differences in overall serum lipids after six weeks, we did notice improvements in several key markers associated with HDL function. The BEE-fed mice exhibited higher levels of beneficial paraoxonase-1 (PON1) activity, which is important for heart health, as well as reductions in liver aspartate transaminase and fasting glucose levels.
Furthermore, the BEE-fed mice had significantly lower levels of a chemokine linked to inflammation, which is beneficial as chronic inflammation can negatively impact cholesterol levels. Most notably, we found reduced total cholesterol levels in the aorta of the elderberry-fed mice, suggesting a slowdown in the progression of atherosclerosis. Overall, this study indicates that black elderberry could potentially help improve HDL function and support the management of high cholesterol as part of a dietary approach.
Read More
Most Useful Reviews
9
Cholesterol reduction
89 people found this helpful
This vitamin has greatly enhanced my mental and physical health. After a few months of taking this supplement, I’ve observed a significant improvement in my mood and energy levels. The effects are noticeable the following day after taking a dose. Additionally, it has aided me in managing my weight and reducing my cholesterol levels.
Read More
0
No effect noted
1 people found this helpful
I find this supplement entirely ineffective; I felt unwell just the same with or without it. It's preferable to purchase zinc separately and take it in a higher dosage during illness, alongside vitamin C in its ascorbate form. Additionally, these pastilles leave an unpleasant aftertaste. I do not recommend purchasing this product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.8
- All Researches
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Read More
9
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
9
We explored the impact of an anthocyanin-rich black elderberry extract on high cholesterol by conducting a study with apoE(-/-) mice, which are a common model for high cholesterol and HDL dysfunction. Over a period of six weeks, these mice received a diet supplemented with this black elderberry extract while a control group maintained a normal diet.
Our findings were quite promising. Although we didn’t see significant differences in overall serum lipids after six weeks, we did notice improvements in several key markers associated with HDL function. The BEE-fed mice exhibited higher levels of beneficial paraoxonase-1 (PON1) activity, which is important for heart health, as well as reductions in liver aspartate transaminase and fasting glucose levels.
Furthermore, the BEE-fed mice had significantly lower levels of a chemokine linked to inflammation, which is beneficial as chronic inflammation can negatively impact cholesterol levels. Most notably, we found reduced total cholesterol levels in the aorta of the elderberry-fed mice, suggesting a slowdown in the progression of atherosclerosis. Overall, this study indicates that black elderberry could potentially help improve HDL function and support the management of high cholesterol as part of a dietary approach.
Our findings were quite promising. Although we didn’t see significant differences in overall serum lipids after six weeks, we did notice improvements in several key markers associated with HDL function. The BEE-fed mice exhibited higher levels of beneficial paraoxonase-1 (PON1) activity, which is important for heart health, as well as reductions in liver aspartate transaminase and fasting glucose levels.
Furthermore, the BEE-fed mice had significantly lower levels of a chemokine linked to inflammation, which is beneficial as chronic inflammation can negatively impact cholesterol levels. Most notably, we found reduced total cholesterol levels in the aorta of the elderberry-fed mice, suggesting a slowdown in the progression of atherosclerosis. Overall, this study indicates that black elderberry could potentially help improve HDL function and support the management of high cholesterol as part of a dietary approach.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cholesterol reduction
89 people found this helpful
This vitamin has greatly enhanced my mental and physical health. After a few months of taking this supplement, I’ve observed a significant improvement in my mood and energy levels. The effects are noticeable the following day after taking a dose. Additionally, it has aided me in managing my weight and reducing my cholesterol levels.
Read More
0
No effect noted
1 people found this helpful
I find this supplement entirely ineffective; I felt unwell just the same with or without it. It's preferable to purchase zinc separately and take it in a higher dosage during illness, alongside vitamin C in its ascorbate form. Additionally, these pastilles leave an unpleasant aftertaste. I do not recommend purchasing this product.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. doi:10.1111/jpn.14091
- Sabar N, Hussain MI, Saleem H, Khan MA, Khalid H, et al. Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients. Pak J Pharm Sci. 2024;37:199.
- Son J, Lee WD, Kim H, Hong EC, Kim HJ, et al. A comparative study on feeding timing and additive types of broilers in a high-temperature environment. J Anim Sci. 2023;101. doi:10.1093/jas/skad290
- Sarkar S, Dey SK, Datta G, Bandyopadhyay A. Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males. Sports Med Health Sci. 2023;5:137. doi:10.1016/j.smhs.2023.03.006
- Darand M, Salehi-Abargouei A, Vahidi Mehrjardi MY, Feizi A, Seyedhossaini SM, et al. Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography. Front Nutr. 2022;9:1097411. doi:10.3389/fnut.2022.1097411
- Omidi S, Bouyeh M, Seidavi A. The effect of vitamin C and aspirin supplementation on the performance of turkeys under normal conditions. Anim Biotechnol. 2023;34:3395. doi:10.1080/10495398.2022.2152037
- Chhina GS, Chhabra A, Luthra SR, Khattar S, Singh P, et al. Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus. Cureus. 2024;16:e69180. doi:10.7759/cureus.69180
- Kimura K, Suzuki F, Tsujiguchi H, Hara A, Miyagi S, et al. Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study. J Nutr Sci. 2024;13:e45. doi:10.1017/jns.2024.26
- Hasani M, Monfared V, Aleebrahim-Dehkordi E, Jafari A, Agh F, et al. The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats. Curr Mol Med. 2024;24:1307. doi:10.2174/0115665240268180231113045836
- Khajeh M, Hassanizadeh S, Pourteymour Fard Tabrizi F, Hassanizadeh R, Vajdi M, et al. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis. Biol Trace Elem Res. 2024;202:4877. doi:10.1007/s12011-024-04059-x
- Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. doi:10.3390/jcm12247650
- Steinbauer S, König A, Neuhauser C, Schwarzinger B, Stangl H, et al. Elder (Sambucus nigra), identified by high-content screening, counteracts foam cell formation without promoting hepatic lipogenesis. Sci Rep. 2024;14:3547. doi:10.1038/s41598-024-54108-7
- Farrell N, Norris G, Lee SG, Chun OK, Blesso CN. Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice. Food Funct. 2015;6:1278. doi:10.1039/c4fo01036a
- Murkovic M, Abuja PM, Bergmann AR, Zirngast A, Adam U, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. 2004;58:244.
